Today you can see some of the tuning options at Euro Truck Simulator 2. On the screenshots are 2 of the 8 options shown.
On the first screen, below, you can see that you can change the chassis, to 4x2, 6x4 of 6x2-4. This is just one of the many options, as you can see:
On the second screen, below, you can see that you can upgrade the interior. Both for left-hand and right-hand side interiors: